Two people with cystic fibrosis dating each other

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And the sorts of bacteria that they share tend to shorten their life span.

Burkholderia and Pseudomonas often lead to chronic airway infections, and Burkholderia usually will preclude a lung transplant.

In people with CF, a defective gene causes a thick, buildup of mucus in the lungs, pancreas and other organs.

People with CF can have a variety of symptoms, including: The defective CF gene contains a slight abnormality called a mutation.

In the late 1990s, the CF Foundation established key programs to help speed development of CF therapies, including a national network of centers designed to conduct clinical trials and share data, and a therapeutics development program to support and govern research collaborations with biotech and pharmaceutical companies.

By pursuing these bold strategies and others, the CF Foundation has built a robust pipeline of potential new therapies that fight the disease from every angle.

And, nearly every CF drug available today was made possible because of Foundation support -- including therapies to treat the underlying cause of the disease.

Learn about the CF Foundation's key research programs.

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